JPI HDHL is pleased to launch a new call to create dedicated, top-class transnational research consortia in the emerging field of nutrition and epigenetics. Previous research has studied epigenetic changes in early life. However, the effects of diet on epigenetic regulation, gene expression in different tissues, and subsequent metabolic health and disease are still unclear. Experts need to better understand the mechanistic pathways that link dietary interventions to those epigenetic changes that have functional/physiological consequences to the tissue and ultimately the organism.

The aim of this call is to support transnational, collaborative research projects that gain a better understanding of the diet-epigenome relationships and their effect on human health. This will allow the development and substantiation of intervention strategies for treating nutrition-related diseases and sustaining good health throughout the life course.

Proposals should focus on diet and epigenome, and cover one of the following areas:

• Establishing cause-and-effect relationships between diet, the epigenome and metabolic health.


• Identifying risk factors and early stage epigenetic changes.


• Epigenetic effects across the lifespan and inter (and potentially trans) generational epigenetic effects.


• Investigation of modifiable factors that could be involved in epigenetic regulation.


• The effect of diet and nutritional status on the intra-uterine environment.

The submission deadline for proposals is the 12^th April 2018 (16:00 CET).

More information in the next link: Call for Joint Action “Nutrition & the Epigenome”